Metsoako ea bohlokoa ea Lihlahisoa tsa Rona
Ashwagandha
Ashwaganda ke setlama sa Ayurvedic se tsejoang hape e le Withania Somnifera se sebelisitsoeng e le pheko e pharalletseng India ka makholo a lilemo (Pratte M et al, 2014).
Setlama se khetholloa e le adaptogen, e bonts'ang bokhoni ba eona ba ho laola lits'ebetso tsa 'mele' me ka tsela eo e tsitsise karabelo ea mmele ho khatello ea maikutlo (Provino R, 2010). Ashwagandha e na le phello ea matšoenyeho liphoofolong le bathong. Phuputso e laoloang ea polokelo ea "placebo" e laoloang habeli ka polokeho le katleho ea methapo ea ashwagandha e nang le mohopolo o phahameng ho fokotsa khatello ea maikutlo le matšoenyeho ho batho ba baholo (Chandrasekhar K et al, 2012) e senotse hore 600mg ea ashwagandha e ntšoa matsatsi a 60 ho batho ba nang le lefu le sa foleng khatello ea kelello e khona ho ntlafatsa likarolo tsohle tse lekiloeng le ho fokotsa serum cortisol ka 27.9%.
Liphuputso li boetse li bonts'a hore ho bile le litlamorao ho ts'oenyeho ho ts'oanang le tsa benzodiazepines tse tloaelehileng (Pratte M et al, 2014). Phuputso ea morao-rao (Lopresti A et al, 2019) e senotse hore ho nka tekanyetso ea letsatsi le letsatsi ea 240 mg ea Ashwagandha ho fokolitse maemo a khatello ea maikutlo a batho ha a bapisoa le placebo. Sena se ne se kenyelletsa maemo a fokotsehileng a cortisol e leng hormone ea khatello ea maikutlo.
Bacopa
Bacopa monnieri ke setlama sa nootropic se 'nileng sa sebelisoa merianeng ea setso bakeng sa bophelo bo bolelele le ntlafatso ea kutloisiso. Ho tlatselletsa Bacopa ho ka fokotsa ho tšoenyeha le ho ntlafatsa mohopolo.
Phuputso ea 2008 (Calabrese C et al, 2008) ka litlamorao tsa kh'outu e emeng ea Bacopa mabapi le ts'ebetso ea ts'ebeliso ea kelello, matšoenyeho le khatello ea maikutlo bathong li senotse ntlafatso e kholo tlhokomelong (ho na le monyetla oa ho ela hloko leseli le sa amaneng), mohopolo oa ho sebetsa le tlase ho tšoenyeha le khatello ea maikutlo. Hape ho ka hlokomeloa ho fokotseha ha sekhahla sa pelo ntle le phetoho ea khatello ea mali.
Ho feta mona phuputso ea morao-rao (Benson S et al, 2013) ho lekola litekanyetso tsa Bacopa mabapi le khatello ea maikutlo le khatello ea maikutlo tse ngata li senotse hore tekanyetso ea 640mg ea setlama e hlahisang phokotso e kholo maemong a cortisol nakong ea lihora tse peli kamora moo ho e nka.
GABA
Gamma-Aminobutyric acid ke amino acid e hlahisoang ka tlhaho bokong. GABA e sebetsa joalo ka neurotransmitter, e thusang puisano lipakeng tsa lisele tsa boko. Karolo e kholo eo GABA ae phethang 'meleng ke ho fokotsa tšebetso ea methapo ea kutlo bokong le sistimi ea methapo e bohareng, e nang le litlamorao tse ngata mmeleng le kelellong, ho kenyeletsoa boikhathollo bo eketsehileng, khatello ea maikutlo e fokotsehileng, khutso le botsitso, ho fokotsa bohloko, le ho matlafatsa boroko.
Karolo ea thibelo ea methapo ea pelo ea GABA esale e nkuoa e le setsi sa taolo ea matšoenyeho mme sistimi ena ea methapo ea kutlo ke sepheo sa benzodiazepines le lithethefatsi tse amanang le eona tse sebelisetsoang ho sebetsana le mathata a ho tšoenyeha (Nuss P, 2015).
L-theanine
L-Theanine ke amino acid e se nang protheine e fumanehang haholo tee e tala e amanang le melemo e 'maloa ea bophelo bo botle ho kenyelletsa ntlafatso ea maikutlo, kutloisiso le phokotso ea matšoao a ts'oanang le matšoenyeho (Everett JM et al, 2016).
Everett JM et al (2016) ba lekotse liteko tse hlano tse laoloang ka tatellano tse kenyelletsang barupeluoa ba 104 ba ikemiselitseng ho sebelisa litonki L-theanines ts'ebetsong mabapi le khatello ea maikutlo le khatello ea maikutlo. Boithuto bo fumane hore ho na le phokotso e hlakileng ea matšoao ana ha thiamine e ne e jeoa letsatsi le letsatsi. Phuputso e tlatselletsang e shebile haholo ho batho ba phelang le maemo a boima joalo ka schizophrenia le schizoaffective disorder. Patlisiso e fumane hore L-theanine e fokotse matšoenyeho le matšoao a ntlafetseng (Ritsner M et al, 2009).
5-HTP
5-HTP (5-hydroxytryptophan) ke sehlahisoa sa lik'hemik'hale sa protheine L-tryptophan. E boetse e hlahisoa ka mokhoa oa khoebo ho tsoa peo ea semela sa Afrika se tsejoang ka hore ke Griffonia simplicifolia.
5-HTP e sebetsa bokong le tsamaisong ea methapo e bohareng ka ho eketsa tlhahiso ea serotonin ea lik'hemik'hale. Serotonin e ka ama boroko, takatso ea lijo, mocheso, boitšoaro ba thobalano le bohloko ba maikutlo. Kaha 5-HTP e eketsa ts'ebeliso ea serotonin, e sebelisetsoa maloetse a 'maloa moo ho lumeloang hore serotonin e bapala karolo ea bohlokoa ho kenyelletsa khatello ea maikutlo, ho hlobaela, botenya le maemo a mang a mangata.
Phuputso e entsoeng ke Pediatr E (2004) e ikemiselitse ho lekola ts'ebeliso ea 5-HTP ho phekola litšabo tsa boroko baneng. Liphetho li fumanoe 2mg / kg ea 5-HTP bakeng sa matsatsi a 20 e ne e amahanngoa le litšabo tse fokolang haholo tsa boroko nakong ea tlatsetso le ho fihlela likhoeli tse 6 kamora moo.
koena
Peppermint (Mentha × piperite) ke setlama se nkhang hamonate lelapeng la koena se sefapano lipakeng tsa lehapu le lerumo. E rata Europe le Asia, e sebeliselitsoe lilemo tse likete bakeng sa tatso ea eona e monate, e monate le melemo ea bophelo bo botle. Peppermint e sebelisetsoa merero e fapaneng empa ea bohlokoa ka ho fetisisa, e bonts'oa ho ntlafatsa boroko (Groves M, 2018).
Tlhahlobo ea bioactivity le melemo e ka bang teng ea bophelo bo botle ba tee ea peppermint (Mckay D le Blumberg J, 2006) e bonts'itse tee ea peppermint hore e be phomolo ea mesifa e ka sebelisoang ho phomola pele ho nako ea ho robala.
Rhodiola
Rhodiola ke setlama se melang libakeng tse batang, tse lithaba tsa Europe le Asia. Metso ea eona e nkuoa e le li-adaptogen, ho bolelang hore li thusa 'mele oa hau ho ikamahanya le khatello ea maikutlo ha o jeoa. Rhodiola e tsejoa hape e le motso oa arctic kapa motso oa khauta, 'me lebitso la eona la mahlale ke Rhodiola rosea (Res P, 2015).
Motso oa sona o na le metsoako e fetang 140 e sebetsang, tse peli tse matla ka ho fetisisa ke rosavin le salidroside. Batho ba Russia le linaheng tsa Scandinavia ba sebelisitse rhodiola ho phekola matšoenyeho, mokhathala le khatello ea maikutlo ka makholo a lilemo.
Phuputso e 'ngoe e batlile litlamorao tsa ho ntša rhodiola ho batho ba 101 ba nang le khatello ea maikutlo e amanang le bophelo le mosebetsi. Barupeluoa ba fuoe 400 mg ka letsatsi libeke tse 'ne (Res, P 2012). E fumane ntlafatso e kholo matšoao a khatello ea maikutlo, joalo ka mokhathala, mokhathala le matšoenyeho, kamora matsatsi a mararo feela. Lintlafatso tsena li ile tsa tsoela pele thutong eohle.
References:
Pratte M, Nanavati K, Young V le Morley C. Phekolo e 'ngoe ea ho Tšoenyeha: Tlhahlobo e Hlophisitsoeng ea Liphetho tsa Teko ea Batho e tlalehiloeng bakeng sa Setlama sa Ayurvedic Ashwagandha (Withania somnifera). J Altern Complement Med, 2014.
Provino R. Karolo ea li-adaptogens taolong ea khatello ea maikutlo. Aust J Med Litlama 2010; 22: 41-49
Bhattacharya S, Muruganandam A. Ketsahalo ea Adaptogenic ea Andania somnifera: thuto ea liteko e sebelisang mofuta oa rat oa khatello ea maikutlo e sa foleng. Pharmacol Biochem Behav 2003; 75: 547-555
Lopresti A, Smith S, Malvi H le Kodgule R. Patlisiso mabapi le liketso tsa khatello le khatello ea meriana ea ashwagandha (Withania somnifera) ntša. Bongaka (Baltimore) 2019.
K Chandrasekhar , Jyoti Kapoor, Sridhar Anishetty. Boithuto bo laoloang ba polokeho bo laoloang ke placebo bo sa sebetseng, bo hlophisitsoeng ka polokeho le katleho ea methapo ea ashwagandha e nang le mohopolo o phahameng ho fokotsa khatello ea maikutlo le matšoenyeho ho batho ba baholo. Moindia J Psychol Med 2012 Jul; 34 (3): 255-62
Calabrese C, Gregory W, Leo M, Kraemer D, Bone K, Oken B (2008) Liphello tsa Bacopa monnieri e lekantsoeng mabapi le ts'ebetso ea kelello, matšoenyeho le khatello ea maikutlo ho batho ba tsofetseng: teko e laoloang ea "placebo" e sa sebetseng. . J Altern Complement Med 2008 Phupu; 14 (6): 707-13.
Benson S, Downey L, Stough C, Wetherell M, Zangara A le Scholey A. Boithuto bo matla, bo foufetseng, bo laoloang ke placebo ba 320 mg le 640 mg ea Bacopa monnieri (CDRI 08) mabapi le khatello ea maikutlo ea khatello ea maikutlo ka bongata le maikutlo. Phytother Res. 2014 Mphalane; 28 (4): 551-9.
Ritsner M, Miodownik C, Ratner Y, Shleifer T, Mar M, Pintov L le Lerner V. L-Theanine e Fokotsa Matšoao a Ntle, a Ts'ebetso, le Matšoenyeho ho bakuli ba nang le Schizophrenia le Schizoaffective Disorder: An 8-Week, Randomized, Double-Blind , Sebaka se Laoloang ke Sebaka, 2-Setsi sa Boithuto. Sengolo sa Clinic Psychiatry. Schizophrenia le Schizoaffective. 2009.
Everett JM, Gunathilake D, Dufficy L, Roach P, Thoas J, Thomas J, Upton D, NAumovski N. Theanine ts'ebeliso, khatello ea maikutlo le matšoenyeho litekong tsa bongaka tsa batho: Tlhahlobo e hlophisehileng. Journal ea Phepo e nepahetseng le Metermediary Metabolism. Vol 4, maqephe 41 - 42. 2016.
Phekolo ea bana E. L -5-Hydroxytryptophan kalafo ea litšabo tsa boroko ho bana. Laeborari ea Naha ea Bongaka. 163 (7): 402-7 2004.
Res P. Litlamorao tsa kalafo le polokeho ea Rhodiola rosea e ntšang WS® 1375 lithutong tse nang le matšoao a khatello ea bophelo - liphetho tsa boithuto bo bulehileng. Laeborari ea Naha ea Bongaka. 26 (8): 1220-5 2012.
Res P. Liphello tsa Rhodiola rosea L. Tlosa ho Tšoenyeha, Khatello ea Kelello, Temoho le Matšoao a Mang a Maemo. Laeborari ea Naha ea Bongaka. 29 (12): 1934-9 (2015).